Trichloroacetyl chloride → 2-Phenylthio-5-trichloroacetylpyrrole

HRID 1980912ノート

反応式

HRID 1980912 の反応式
[C:1]1([S:7][C:8]2[NH:9][CH:10]=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:13][C:14]([Cl:19])([Cl:18])[C:15](Cl)=[O:16]>C(Cl)Cl>[C:1]1([S:7][C:8]2[NH:9][C:10]([C:15](=[O:16])[C:14]([Cl:19])([Cl:18])[Cl:13])=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 2

HCID 6420Trichloroacetyl chlorideHCID 127893912-Phenylthiopyrrole

生成物 1

HCID 204009762-Phenylthio-5-trichloroacetylpyrrole

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

2-Phenylthiopyrrole (1.75 g., 10 mmoles) was dissolved in 20 ml. of methylene chloride. Trichloroacetyl chloride (1.1 ml., 10 mmoles) was added and the reaction stirred for 3 hours at room temperature. The reaction mixture was washed with 20 ml. of water and concentrated to yield 2-phenylthio-5-trichloroacetylpyrrole, used directly in the next step.

後処理

  1. washThe reaction mixture was washed with 20 ml
  2. concentrationof water and concentrated

出典と根拠

ORDレコード
ord-e9b1da26447a461ead5b28ddce962ba5
出典データセット
uspto-grants-1985_04
特許番号
US04511575

反応ノート

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