Acetic Anhydride → 9-Acetoxy-3,4-diazatricyclo[4,2,1,02,5]nona-3,7-diene
反応式
[OH:1][CH:2]1[CH:8]2[CH:9]=[CH:10][CH:3]1[CH:4]1[CH:7]2[N:6]=[N:5]1.[C:11](OC(=O)C)(=[O:13])[CH3:12].C(N(CC)CC)C>CCOCC>[C:11]([O:1][CH:2]1[CH:8]2[CH:9]=[CH:10][CH:3]1[CH:4]1[CH:7]2[N:6]=[N:5]1)(=[O:13])[CH3:12]参加物
5
実験手順
5 parts of 9-hydroxy-3,4-diazatricyclo[4,2,1,02,5 ]nona-3,7-diene, 5 parts of acetic anhydride, 1 part of triethylamine and 100 parts of ether were refluxed for 24 hours, after which the reaction mixture was extracted twice with 50 parts of water, and the organic phase was dried with MgSO4 and evaporated down in a rotary evaporator to give 6.2 parts (95 mole %) of 9-acetoxy-3,4-diazatricyclo[4,2,1,02,5 ]nona-3,7-diene of melting point 58° C.
後処理
- extractionafter which the reaction mixture was extracted twice with 50 parts of water
- dry with materialthe organic phase was dried with MgSO4
- customevaporated down in a rotary evaporator
出典と根拠
- ORDレコード
- ord-37b2695f948348a188a8a1879465d1f0
- 出典データセット
- uspto-grants-1985_04
- 特許番号
- US04512795
反応ノート
読み込み中…