Water → Methyl 2-amino-2-phenylpropanoate

HRID 1981236ノート

反応式

HRID 1981236 の反応式
Cl.[NH2:2][C:3]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)([CH3:7])[C:4]([OH:6])=[O:5].O.[CH3:15]COCC>C(N(CC)CC)C>[NH2:2][C:3]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)([CH3:7])[C:4]([O:6][CH3:15])=[O:5]

参加物

5

反応物 3

HCID 962WaterHCID 3283Diethyl EtherHCID 200864462-Amino-2-phenylpropanoic acid hydrochloride

生成物 1

HCID 14426739Methyl 2-amino-2-phenylpropanoate

試薬・触媒・溶媒 1

HCID 8471Triethylamine溶媒

反応条件

温度
20 °C

実験手順

A mixture of 4.3 g of methyl DL aminophenylpropanoate hydrochloride, 43 ml of demineralized water, 86 ml of ether and 3 ml of triethylamine was stirred at 20° C. for 10 minutes and the aqueous phase was extracted with ether. The combined ether phases were dried and evaporated to dryness under reduced pressure to obtain 8.3 g of methyl aminophenylpropanoate.

後処理

  1. extractionthe aqueous phase was extracted with ether
  2. dry with materialThe combined ether phases were dried
  3. customevaporated to dryness under reduced pressure

出典と根拠

ORDレコード
ord-ec0bcd55ae48438697719f4415bf78fc
出典データセット
uspto-grants-1985_04
特許番号
US04513139

反応ノート

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