Ammonia → α-Phenyl-2-benzothiazolemethanamine

HRID 1981460ノート

反応式

HRID 1981460 の反応式
Cl.[NH2:2][CH:3]([C:10]1[S:11][C:12]2[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=2[N:14]=1)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.N>C(Cl)Cl>[NH2:2][CH:3]([C:10]1[S:11][C:12]2[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=2[N:14]=1)[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

参加物

4

反応物 2

HCID 222AmmoniaHCID 23318519HCID 23318519、化合物

生成物 1

HCID 13342005α-Phenyl-2-benzothiazolemethanamine

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

The hydrochloride was stirred with aqueous ammonia and methylene chloride, and the aqueous layer was extracted with two portions of methylene chloride. The combined methylene chloride extracts were washed with brine, dried over Na2SO4, filtered and concentrated in vacuo. 13.1 g of white solid, as desired product, was obtained, mp. 68°-70° C.

後処理

  1. extractionthe aqueous layer was extracted with two portions of methylene chloride
  2. washThe combined methylene chloride extracts were washed with brine
  3. dry with materialdried over Na2SO4
  4. filtrationfiltered
  5. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-5808603c1b1743d2b9708677bca3ab96
出典データセット
uspto-grants-1986_06
特許番号
US04592774

反応ノート

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