Sulfuric Acid → N(m-propionamidophenyl)-2,2-dimethylsuccinimide

HRID 1982078ノート

反応式

HRID 1982078 の反応式
S(=O)(=O)(O)O.[NH2:6][C:7]1[CH:8]=[C:9]([N:13]2[C:17](=[O:18])[CH2:16][C:15]([CH3:20])([CH3:19])[C:14]2=[O:21])[CH:10]=[CH:11][CH:12]=1>C(OC(=O)CC)(=O)CC.O>[C:17]([NH:6][C:7]1[CH:8]=[C:9]([N:13]2[C:17](=[O:18])[CH2:16][C:15]([CH3:19])([CH3:20])[C:14]2=[O:21])[CH:10]=[CH:11][CH:12]=1)(=[O:18])[CH2:16][CH3:15]

参加物

5

反応物 2

HCID 1118Sulfuric AcidHCID 13189216N-m-AMINOPHENYL-2,2-DIMETHYLSUCCINIMIDE

生成物 1

HCID 23317140N(m-propionamidophenyl)-2,2-dimethylsuccinimide

試薬・触媒・溶媒 2

HCID 31263Propionic anhydride触媒HCID 962Water溶媒

実験手順

Five and one half g. of propionic anhydride containing one drop of concentrated sulfuric acid was mixed at ambient temperature with 8.7 g. of N-m-aminophenyl-2,2-dimethylsuccinimide in a small beaker. The mixture became very hot and on cooling was poured into water and extracted with methylene chloride, which was dried and stripped under vacuum yielding 9.5 g. of a glassy product. The product was identified as the title compound by analysis of infrared spectra.

後処理

  1. temperatureon cooling
  2. extractionextracted with methylene chloride, which
  3. customwas dried
  4. customyielding 9.5 g

出典と根拠

ORDレコード
ord-2cf23612caed45fb91d44532bc23b0cb
出典データセット
uspto-grants-1986_06
特許番号
US04595408

反応ノート

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