Sulfuric Acid → Benzylsulfamic acid

HRID 1982164ノート

反応式

HRID 1982164 の反応式
[CH2:1]([N:8]=C=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:11](=O)(=[O:14])([OH:13])[OH:12]>[N+](C)([O-])=O>[CH2:1]([NH:8][S:11](=[O:13])(=[O:12])[OH:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 1118Sulfuric AcidHCID 76639Benzyl isocyanate

生成物 1

HCID 12649342Benzylsulfamic acid

試薬・触媒・溶媒 1

HCID 6375Nitromethane溶媒

実験手順

Benzylisocyanate (13.3 g) is added dropwise to a stirred mixture of nitromethane (160 ml) and 15% fuming sulfuric acid (5.4 ml) at about 10° C. The reaction mixture is refluxed for about one hour, cooled to RT and the solid filtered and washed with nitromethene. The solid is suspended in ether, filtered, dried and used as a crude solid in the next step.

後処理

  1. temperatureThe reaction mixture is refluxed for about one hour
  2. filtrationthe solid filtered
  3. washwashed with nitromethene
  4. filtrationfiltered
  5. customdried

出典と根拠

ORDレコード
ord-c811b7d3305548a083ba6b5e2443a7a8
出典データセット
uspto-grants-1986_06
特許番号
US04595683

反応ノート

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