Hydrochloric Acid → 1-(2-Bromoethyl)-4-(methoxymethyl)benzene
反応式
[Br:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][OH:11])=[CH:6][CH:5]=1.[C:12]1(S(OC)(=O)=O)C=CC=CC=1.C([O-])([O-])=O.[K+].[K+].Cl>CO>[CH3:12][O:11][CH2:10][C:7]1[CH:8]=[CH:9][C:4]([CH2:3][CH2:2][Br:1])=[CH:5][CH:6]=1参加物
6
実験手順
The 1-(2-bromoethyl)-4-hydroxymethylbenzene (0.5 g) is then added to a solution of 0.44 g methyl benzenesulfonate and 0.32 g K2CO3 in 10 ml of methanol and allowed to react for 4 h. The solution is neutralized with methanolic HCl and extracted with ether. The ether extract is dried over Na2SO4, filtered, and the solvent removed under vacuum to yield 1-(methoxymethyl)-4-(2-bromoethyl)benzene (13).
後処理
- customto react for 4 h
- extractionextracted with ether
- extractionThe ether extract
- dry with materialis dried over Na2SO4
- filtrationfiltered
- customthe solvent removed under vacuum
出典と根拠
- ORDレコード
- ord-5b068b583436409eabd006459c3eab5d
- 出典データセット
- uspto-grants-1986_06
- 特許番号
- US04595690
反応ノート
読み込み中…