Carbon Dioxide → HCID 178484730、化合物
反応式
[N:1](C(OCC1C=CC=CC=1)=O)([CH2:3][C:4]([NH:6][C@H:7]([C:14]([NH:16][C@H:17]([C:30]([O:32][CH3:33])=[O:31])[CH2:18][CH2:19][CH2:20][CH2:21][NH:22][C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])=[O:15])[CH2:8][C:9]1[N:13]=[CH:12][NH:11][CH:10]=1)=[O:5])[CH3:2].C(=O)=O>CO>[NH:1]([CH2:3][C:4]([NH:6][C@H:7]([C:14]([NH:16][C@H:17]([C:30]([O:32][CH3:33])=[O:31])[CH2:18][CH2:19][CH2:20][CH2:21][NH:22][C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])=[O:15])[CH2:8][C:9]1[N:13]=[CH:12][NH:11][CH:10]=1)=[O:5])[CH3:2]参加物
4
実験手順
390 mg of Z-Sar-His-Lys(Boc)-OMe are dissolved in 10 ml of 95% strength MeOH and, after the addition of 40 mg of Pd-on-carbon, hydrogenated with CO2 -absorption until saturation. The catalyst is filtered off, the filtrate is concentrated to dryness and the amorphous residue is dried to constant weight in a high vacuum at 40°, yielding H-Sar-His-Lys(Boc)-OMe; Rf (G)=0.1; Rf (E)=0.25.
後処理
- filtration