(2-Amino-1,3-thiazol-4-yl)acetic acid → HCID 13575153、化合物
反応式
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([OH:10])=O)[N:6]=1.[NH2:11][C@H:12]1[CH2:15][N:14]([S:16]([OH:19])(=[O:18])=[O:17])[C:13]1=[O:20]>>[NH2:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([NH:11][C@H:12]2[CH2:15][N:14]([S:16]([OH:19])(=[O:18])=[O:17])[C:13]2=[O:20])=[O:10])[N:6]=1参加物
3
実験手順
Following the procedure of Example 1 but substituting an equivalent amount of 2-amino-4-thiazoleacetic acid for the formyl protected reactant and (3S)-3-amino-2-oxo-1-azetidinesulfonic acid, inner salt for the 4-methyl reactant, one obtains as a result of the enzymatic coupling (3S)-3-[[[2-amino-4-thiazolyl]acetyl]amino]-2-oxo-1-azetidinesulfonic acid, zwitterion. Again, the structure is confirmed by analytical and bioassay techniques.
後処理
- customobtains as
出典と根拠
- ORDレコード
- ord-b32735d072b949cab7a00bfb46b57e5c
- 出典データセット
- uspto-grants-1986_06
- 特許番号
- US04596777
反応ノート
読み込み中…