8-Phenyl-5,6-dihydroimidazo[1,2-a]pyridine → 8-Phenylimidazo[1,2-a]pyridine

HRID 1982531

反応式

HRID 1982531 の反応式
[C:1]1([C:7]2[C:8]3[N:9]([CH:13]=[CH:14][N:15]=3)[CH2:10][CH2:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[C:1]1([C:7]2[C:8]3[N:9]([CH:13]=[CH:14][N:15]=3)[CH:10]=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 1

HCID 137640128-Phenyl-5,6-dihydroimidazo[1,2-a]pyridine

生成物 1

HCID 137640278-Phenylimidazo[1,2-a]pyridine

試薬・触媒・溶媒 2

HCID 178418406HCID 178418406、化合物触媒HCID 6344Dichloromethane溶媒

実験手順

Combine 9 g (46 mmol) of the product from Example 3 with 50 g of "activated" manganese dioxide in 200 ml of methylene chloride, and heat to reflux for 8 hr. Filter off the solids and remove the solvent in vacuo. Crystallize the residue from ether to provide the title compound.

後処理

  1. temperatureto reflux for 8 hr
  2. filtrationFilter off the solids
  3. customremove the solvent in vacuo
  4. customCrystallize the residue from ether

出典と根拠

ORDレコード
ord-9400b12782584027a228e333df8d0875
出典データセット
uspto-grants-1986_06
特許番号
US04596872

関連ノート

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