Hydrochloric Acid → 2-(6-Aminopyridin-2-yl)-2-methoxyiminoacetic acid hydrochloride
反応式
C([NH:3][C:4]1[N:9]=[C:8]([C:10](=[N:14][O:15][CH3:16])[C:11]([OH:13])=[O:12])[CH:7]=[CH:6][CH:5]=1)=O.[ClH:17]>CO>[ClH:17].[NH2:3][C:4]1[N:9]=[C:8]([C:10](=[N:14][O:15][CH3:16])[C:11]([OH:13])=[O:12])[CH:7]=[CH:6][CH:5]=1参加物
4
実験手順
A suspension of 2-(6-formamidopyridin-2-yl)-2-methoxyiminoacetic acid (1.5 g.) and conc. hydrochloric acid (0.77 g.) in methanol (30 ml.) was stirred at room temperature for 45 minutes. After concentrating the resultant solution under reduced pressure, the residue was washed with diethyl ether. The precipitates were collected by filtration to give 2-(6-aminopyridin-2-yl)-2-methoxyiminoacetic acid hydrochloride (1.63 g.), mp 100° to 105° C.
後処理
- concentrationAfter concentrating the resultant solution under reduced pressure
- washthe residue was washed with diethyl ether
- filtrationThe precipitates were collected by filtration
出典と根拠
- ORDレコード
- ord-4e89a046ecac483a84cfe3b542c41f84
- 出典データセット
- uspto-grants-1986_06
- 特許番号
- US04596869
反応ノート
読み込み中…