HCID 57710680、化合物 → Bis(4-isopropylphenyl)amine

HRID 1982744ノート

反応式

HRID 1982744 の反応式
C([N:4]([C:14]1[CH:19]=[CH:18][C:17]([CH:20]([CH3:22])[CH3:21])=[CH:16][CH:15]=1)[C:5]1[CH:10]=[CH:9][C:8]([CH:11]([CH3:13])[CH3:12])=[CH:7][CH:6]=1)(=O)C>C(O)C>[CH:20]([C:17]1[CH:18]=[CH:19][C:14]([NH:4][C:5]2[CH:6]=[CH:7][C:8]([CH:11]([CH3:13])[CH3:12])=[CH:9][CH:10]=2)=[CH:15][CH:16]=1)([CH3:22])[CH3:21]

参加物

3

反応物 1

HCID 57710680HCID 57710680、化合物

生成物 1

HCID 14762646Bis(4-isopropylphenyl)amine

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

N-Acetyl-N,N-di(4-isopropylphenyl)amine (5.4 g, 18.4 mmol) are heated to reflux in 100 ml of 20% aqueous ethanol. The reaction is monitored by thin-layer chromatography. After 30 h, no reactant is any longer detectable in the TLC. The ethanolic solution is poured into dist. water, and the brownish precipitate is filtered off with suction, dissolved in dichloromethane and dried with sodium sulphate. The solution is concentrated and chromatographed through a short silica gel column with 50% dichloromethane in hexane. The product fractions are concentrated to dryness and the product is dried under reduced pressure.

後処理

  1. additionThe ethanolic solution is poured into dist
  2. filtrationwater, and the brownish precipitate is filtered off with suction
  3. dissolutiondissolved in dichloromethane
  4. dry with materialdried with sodium sulphate
  5. concentrationThe solution is concentrated
  6. customchromatographed through a short silica gel column with 50% dichloromethane in hexane
  7. concentrationThe product fractions are concentrated to dryness
  8. customthe product is dried under reduced pressure

出典と根拠

ORDレコード
ord-8826973177f346569a29a8230f5bbb3c
出典データセット
uspto-grants-2009_06
特許番号
US07540978B2

反応ノート

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