Benzyl Bromide → HCID 11618156、化合物
反応式
[F:1][C:2]1[CH:20]=[CH:19][C:5]([CH2:6][NH:7][C:8]2[C:9]3[NH:16][C:15]([CH3:17])=[C:14]([CH3:18])[C:10]=3[CH:11]=[N:12][CH:13]=2)=[CH:4][CH:3]=1.[ClH:21].F[C:23]1[CH:41]=[CH:40][C:26]([CH2:27]NC2C3NC(C)=C(C)C=3C=NC=2)=[CH:25][CH:24]=1.C(=O)(O)[O-].[Na+].C(Br)C1C=CC=CC=1>>[ClH:21].[CH2:27]([N:16]1[C:9]2[C:8]([NH:7][CH2:6][C:5]3[CH:19]=[CH:20][C:2]([F:1])=[CH:3][CH:4]=3)=[CH:13][N:12]=[CH:11][C:10]=2[C:14]([CH3:18])=[C:15]1[CH3:17])[C:26]1[CH:40]=[CH:41][CH:23]=[CH:24][CH:25]=1参加物
5
実験手順
In accordance with the same procedures as in Example 2, except for using 7-(4-fluorobenzylamino)-2,3-dimethyl-1H-pyrrolo[3,2-c]pyridine obtained by treating the compound of Example 23 with a saturated sodium bicarbonate solution and benzyl bromide, the titled compound was obtained as a white solid. (Yield: 15.8% )