Imidazole → HCID 19854577、化合物
反応式
CC1C=CC(S(O[CH2:12][CH2:13][C:14]#[CH:15])(=O)=O)=CC=1.[NH:16]1[CH:20]=[CH:19][N:18]=[CH:17]1.C([O-])([O-])=O.[K+].[K+].C(Cl)Cl>CC(=O)CC.O>[CH2:12]([N:16]1[CH:20]=[CH:19][N:18]=[CH:17]1)[CH2:13][C:14]#[CH:15]参加物
7
実験手順
A mixure of but-3-ynyl 4-methylbenzenesulfonate (1.04 g), imidazole (573 mg) and K2CO3 (3.88 g) in 2-butanone (10 mL) was heated to reflux overnight. Work-up (DCM, H2O), drying (Na2SO4) and concentration gave 1-(but-3-ynyl)-1H-imidazole (501 mg).
後処理
- temperatureto reflux overnight
- customdrying
- concentration(Na2SO4) and concentration
出典と根拠
- ORDレコード
- ord-d98c0b1ef83c4f88b903e1fe780e1065
- 出典データセット
- uspto-grants-2009_06
- 特許番号
- US07544672B2
反応ノート
読み込み中…