2-[4-(4-Methoxyphenyl)piperazin-1-yl]ethanamine → 3-{2-[4-(4-Methoxyphenyl)piperazin-1-yl]ethyl}aminomethyl-5-methyl-1-phenylpyrazole

HRID 1984156ノート

反応式

HRID 1984156 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][NH2:17])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1.[CH3:18][C:19]1[N:23]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[N:22]=[C:21]([CH:30]=O)[CH:20]=1>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([N:9]2[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][NH:17][CH2:30][C:21]3[CH:20]=[C:19]([CH3:18])[N:23]([C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)[N:22]=3)[CH2:13][CH2:14]2)=[CH:7][CH:8]=1

参加物

3

反応物 2

HCID 12561082-[4-(4-Methoxyphenyl)piperazin-1-yl]ethanamineHCID 141352365-Methyl-1-phenylpyrazole-3-carbaldehyde

生成物 1

HCID 160386373-{2-[4-(4-Methoxyphenyl)piperazin-1-yl]ethyl}aminomethyl-5-methyl-1-phenylpyrazole収率 22.1%

実験手順

Compound 37 was prepared using the same method as that of Example 1 except that 4-(4-methoxyphenyl)piperazin-1-ylethylamine and 5-methyl-1-phenylpyrazole-3-carbaldehyde were used.

出典と根拠

ORDレコード
ord-86e455b50ad1429ea5df356f17b40dfe
出典データセット
uspto-grants-2009_06
特許番号
US07544686B2

反応ノート

読み込み中…