1,5-Dimethyl-1H-pyrazole-3-carboxamide → 1,5-dimethyl-1H-pyrazole-3-carbonitrile
反応式
[CH3:1][N:2]1[C:6]([CH3:7])=[CH:5][C:4]([C:8]([NH2:10])=O)=[N:3]1>P(Cl)(Cl)(Cl)=O>[CH3:1][N:2]1[C:6]([CH3:7])=[CH:5][C:4]([C:8]#[N:10])=[N:3]1参加物
3
実験手順
The method described in Part E of Examples 1 through 4 was used to treat 1,5-dimethyl-1H-pyrazole-3-carboxamide (5.0 g, 36 mmol) with phosphorous oxychloride (20 mL) to afford 3.9 g of 1,5-dimethyl-1H-pyrazole-3-carbonitrile. A small portion was recrystallized from hexane to provide the following data.
出典と根拠
- ORDレコード
- ord-cc9e00bed9c840ef9d4a4dfb3bb41681
- 出典データセット
- uspto-grants-2009_06
- 特許番号
- US07544697B2
反応ノート
読み込み中…