Methanol → HCID 66894422、化合物
反応式
[NH2:1][C@@H:2]([CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[Cl:13])[C:3]([OH:5])=[O:4].[CH3:14]O>>[ClH:13].[CH3:14][O:4][C:3](=[O:5])[C@@H:2]([NH2:1])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[Cl:13]参加物
3
実験手順
2(S)-Amino-3-(2-chlorophenyl)propionic acid (1 g, commercially available) was dissolved in methanol (10 mL) and HCl gas was bubbled through the solution for 5 min. The reaction mixture was stirred at room temperature for 3 h and the solvent was evaporated using the rotavap to get 2(S)-amino-3-(2-chlorophenyl)propionic acid methyl ester hydrochloride (1.2 g).
後処理
- customHCl gas was bubbled through the solution for 5 min
- customthe solvent was evaporated
出典と根拠
- ORDレコード
- ord-b21c25fc386f40ea977dd0f731e0f883
- 出典データセット
- uspto-grants-2009_06
- 特許番号
- US07547701B2
反応ノート
読み込み中…