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3-Isobutyl-1-methylxanthine → N7-bromoehtyl 3-isobutyl-1-methylxanthine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Isobutyl-1-methylxanthine | HCID 3758 | — |
| 反応物 | 2-Bromoethylamine | HCID 7851 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | N7-bromoehtyl 3-isobutyl-1-methylxanthine | HCID 69056164 | — |
反応手順
The process of preparing the compound of formula I comprises the steps of dissolving 3-isobutyl-1-methylxanthine (IBMX) into methanol and stirring with 2-bromoethylamine upon a mantle heater, reacting this mixture with NaOH and then recrystallizing this mixture with methanol to obtain N7-bromoehtyl 3-isobutyl-1-methylxanthine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07550468B2 |
| 出典データセット | uspto-grants-2009_06 |
| ORD ID | ord-2844dad69a4b4a888264a6e4aab7ae9d |
| 出典メモ | uspto-grants-2009_06 |