3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole → 1-({4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}methyl)-2-pyrrolidinone
反応式
I[C:2]1[CH:7]=[CH:6][C:5]([CH2:8][N:9]2[CH2:13][CH2:12][CH2:11][C:10]2=[O:14])=[CH:4][CH:3]=1.[F:15][C:16]([F:27])([F:26])[C:17]1[C:25]2[CH2:24][CH2:23][CH2:22][CH2:21][C:20]=2[NH:19][N:18]=1>>[F:27][C:16]([F:15])([F:26])[C:17]1[C:25]2[CH2:24][CH2:23][CH2:22][CH2:21][C:20]=2[N:19]([C:2]2[CH:7]=[CH:6][C:5]([CH2:8][N:9]3[CH2:13][CH2:12][CH2:11][C:10]3=[O:14])=[CH:4][CH:3]=2)[N:18]=1参加物
3
実験手順
The title compound was prepared from 1-[(4-iodophenyl)methyl]-2-pyrrolidinone and 3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole using a similar procedure to that described for Example 19.
出典と根拠
- ORDレコード
- ord-ea8251db3a5e4d13b7a956ca5e6a011f
- 出典データセット
- uspto-grants-2010_01
- 特許番号
- US07642256B2