Hydrazine → HCID 23153686、化合物
反応式
[NH2:1][NH2:2].[CH3:3][O:4][C:5]1[N:10]=[CH:9][C:8]([C:11]([C:13]2[CH:21]=[CH:20][CH:19]=[CH:18][C:14]=2[C:15](O)=[O:16])=O)=[CH:7][CH:6]=1>C(O)C>[CH3:3][O:4][C:5]1[N:10]=[CH:9][C:8]([C:11]2[C:13]3[C:14](=[CH:18][CH:19]=[CH:20][CH:21]=3)[C:15](=[O:16])[NH:2][N:1]=2)=[CH:7][CH:6]=1参加物
4
反応条件
- 温度
- 60 °C
実験手順
24 ml (121 mmol) of hydrazine was added to an ethanol solution (200 ml) of 28.0 g of 2-[(6-methoxypyridin-3-yl)carbonyl]benzoic acid, and the reaction liquid was stirred at 60° C. for 4 hours. The reaction liquid was concentrated under reduced pressure, and the resulting solid was washed with diethyl ether to obtain 21.50 g (yield: 77%) of 4-(6-methoxypyridin-3-yl)-2H-phthalazin-1-on as a white solid.
後処理
- customthe reaction liquid
- customThe reaction liquid
- concentrationwas concentrated under reduced pressure
- washthe resulting solid was washed with diethyl ether
出典と根拠
- ORDレコード
- ord-eec588994129415791885f99e37dbced
- 出典データセット
- uspto-grants-2010_01
- 特許番号
- US07645756B2
反応ノート
読み込み中…