4-Chloro-3-methylbenzaldehyde → 4-[(4-Formyl-2-methylphenyl)sulfanyl]-2,5-dimethylphenoxy-acetic acid ethyl ester

反応式

C(OC(=O)COC1C=CC(SC2C=CC(C=O)=CC=2)=CC=1C)C.[CH2:24]([O:26][C:27](=[O:39])[CH2:28][O:29][C:30]1[CH:35]=[C:34]([CH3:36])[C:33]([SH:37])=[CH:32][C:31]=1[CH3:38])[CH3:25].Cl[C:41]1[CH:48]=[CH:47][C:44]([CH:45]=[O:46])=[CH:43][C:42]=1[CH3:49]>>[CH2:24]([O:26][C:27](=[O:39])[CH2:28][O:29][C:30]1[CH:35]=[C:34]([CH3:36])[C:33]([S:37][C:41]2[CH:48]=[CH:47][C:44]([CH:45]=[O:46])=[CH:43][C:42]=2[CH3:49])=[CH:32][C:31]=1[CH3:38])[CH3:25]

参加物

反応物 3

HCID 27576594-Chloro-3-methylbenzaldehyde

HCID 207681072,5-Dimethyl-4-mercaptophenoxy-acetic acid ethyl ester

HCID 207681214-[(4-Formylphenyl)sulfanyl]-2-methylphenoxy-acetic acid ethyl ester

生成物 1

HCID 207681204-[(4-Formyl-2-methylphenyl)sulfanyl]-2,5-dimethylphenoxy-acetic acid ethyl ester

実験手順

The title compound was prepared according to the method described for preparing compound 7.1, using compound 21.3 and 4-chloro-3-methylbenzaldehyde as the starting materials. 1H NMR (400 MHz) (CDCl3) δ 9.86 (1H, s); 7.62 (1H, s); 7.44 (1H, d, J=8.1 Hz); 7.33 (1H, s); 6.70 (1H, s); 6.62 (1H, d, J=8.1 Hz); 4.68 (2H, s); 4.29 (2H, q, J=7.1 Hz); 2.46 (3H, s); 2.29 (3H, s); 2.26 (3H, s); 1.32 (3H, t, J=7.1 Hz).