Ethyl pyruvate → ethyl (2E)-2-[(3-nitrophenyl)hydrazinylidene]propanoate

HRID 1991754ノート

反応式

HRID 1991754 の反応式
Cl.[N+:2]([C:5]1[CH:6]=[C:7]([NH:11][NH2:12])[CH:8]=[CH:9][CH:10]=1)([O-:4])=[O:3].[CH2:13]([O:15][C:16](=[O:20])[C:17](=O)[CH3:18])[CH3:14]>C(O)C>[N+:2]([C:5]1[CH:6]=[C:7]([NH:11]/[N:12]=[C:17](\[CH3:18])/[C:16]([O:15][CH2:13][CH3:14])=[O:20])[CH:8]=[CH:9][CH:10]=1)([O-:4])=[O:3]

参加物

4

反応物 2

HCID 12041Ethyl pyruvateHCID 54642853-Nitrophenylhydrazinium(1+) chloride

生成物 1

HCID 5357576ethyl (2E)-2-[(3-nitrophenyl)hydrazinylidene]propanoate

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

(3-Nitrophenyl)hydrazine hydrochloride (30 g, 0.16 mol) and 2-oxo-propionic acid ethyl ester (22 g, 0.19 mol) were dissolved in ethanol (300 mL). The mixture was stirred at room temperature for 4 h before the solvent was evaporated under reduced pressure to give (E)-ethyl 2-(2-(3-nitrophenyl)hydrazono)propanoate, which was used directly in the next step.

後処理

  1. customwas evaporated under reduced pressure

出典と根拠

ORDレコード
ord-fa32fe6939404a4cbbd78e1db0a87a6b
出典データセット
uspto-grants-2010_01
特許番号
US07645789B2

反応ノート

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