化工社化工社 化学情報印刷レポート · 研究参考用
Cyclopropylamine → 2-Chloro-4-fluoro-5-[(cyclopropylamino)sulfonyl]benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyclopropylamine | HCID 69828 | — |
| 反応物 | 3-(Chlorosulfonyl)-4-fluorobenzoic acid | HCID 3929891 | — |
| 反応物 | 2-Chloro-5-[(ethylamino)sulfonyl]-4-fluorobenzoic acid | HCID 58728052 | — |
| 生成物 | 2-Chloro-4-fluoro-5-[(cyclopropylamino)sulfonyl]benzoic acid | HCID 58728329 | — |
反応手順
1.005 g (3.6 mmol) 3-chlorosulfonyl-4-fluorobenzoic acid was added to 0.76 mL (10.9 mmol) cyclopropylamine following the general procedure in for 2-chloro-5-[(ethylamino)sulfonyl]-4-fluorobenzoic acid. Crude product was used in subsequent step without further purification
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07645771B2 |
| 出典データセット | uspto-grants-2010_01 |
| ORD ID | ord-a951a2a29afa4151a97c8004fedd0b81 |
| 出典メモ | uspto-grants-2010_01 |