N-methyl-2-pyrrolidone → HCID 72988237、化合物
反応式
[CH3:1][O:2][CH:3]([O:20][CH3:21])[CH2:4][CH:5]1[C:9](=[O:10])[CH2:8][CH2:7][CH:6]1[CH:11](C(OC)=O)[C:12]([O:14][CH3:15])=[O:13].CN1C(=O)CCC1>O>[CH3:1][O:2][CH:3]([O:20][CH3:21])[CH2:4][CH:5]1[C:9](=[O:10])[CH2:8][CH2:7][CH:6]1[CH2:11][C:12]([O:14][CH3:15])=[O:13]参加物
4
実験手順
In a 3-neck 250 ml round bottom flask equipped with a short path distillation apparatus, a solution of 80.0 g of dimethyl [2-(2,2-dimethoxyethyl)-3-oxocyclopentyl]malonate and 63.0 g NMP was heated to 160° C. The solution was then charged with water until the reaction was complete. Upon completion of the reaction, distillation under vacuum (b.p.=140-145° C. at 1 mbar) of the reaction medium allowed to recover directly the purified title compound with a yield of 81%.
後処理
- customIn a 3-neck 250 ml round bottom flask equipped with a short path distillation apparatus
- customUpon completion of the reaction, distillation under vacuum (b.p.=140-145° C. at 1 mbar) of the reaction medium
- customto recover directly the
- custompurified title compound with a yield of 81%
出典と根拠
- ORDレコード
- ord-19597ef50be54893ac27967911088bd7
- 出典データセット
- uspto-grants-2010_01
- 特許番号
- US07649107B2
反応ノート
読み込み中…