Acetic Acid → HCID 73045052、化合物
反応式
CC(O)=O.C[O:6][CH:7](OC)[CH2:8][CH:9]1[C:13](=[O:14])[CH2:12][CH2:11][CH:10]1[CH2:15][C:16]([O:18][CH3:19])=[O:17]>O>[O:14]=[C:13]1[CH2:12][CH2:11][CH:10]([CH2:15][C:16]([O:18][CH3:19])=[O:17])[CH:9]1[CH2:8][CH:7]=[O:6]参加物
4
反応条件
- 温度
- 45 °C
実験手順
In a 4 liter jacketed reactor, a mixture of 1,236 liter of AcOH and 1,236 liter of water was heated to 45° C. Then to this mixture were added 494 g of methyl [2-(2,2-dimethoxyethyl)-3-oxocyclopentyl]acetate. The resulting reaction medium was stirred at 46-49° C. until completion of the conversion of the acetal to aldehyde. Distillation under vacuum allowed for the direct isolation of the purified title compound with a yield of 89% (overall yield from Example 1: 66%).
後処理
- customThe resulting reaction medium
- distillationDistillation under vacuum
- custompurified title compound
- customwith a yield of 89% (overall yield from Example 1: 66%)
出典と根拠
- ORDレコード
- ord-5e135179bcae49fcac40dbc5b1a87269
- 出典データセット
- uspto-grants-2010_01
- 特許番号
- US07649107B2
反応ノート
読み込み中…