Propionyl chloride → N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]propanamide
反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([CH3:13])[C:11]([C:14]#[N:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[C:16](Cl)(=[O:19])[CH2:17][CH3:18]>>[C:14]([C:11]1[N:12]([CH3:13])[C:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:1][C:16](=[O:19])[CH2:17][CH3:18])=[CH:3][CH:4]=2)=[CH:9][CH:10]=1)#[N:15]参加物
3
実験手順
The title compound was prepared according to the general procedure for acylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using propionyl chloride (48 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]propanamide (0.012 g).
後処理
- customThe title compound was prepared
出典と根拠
- ORDレコード
- ord-7acc845a84794d0ea0b98a35c60e3433
- 出典データセット
- uspto-grants-2010_01
- 特許番号
- US07652062B2
反応ノート
読み込み中…