HCID 88662971、化合物 → HCID 70436618、化合物

HRID 1995047ノート

反応式

HRID 1995047 の反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]([NH:9][CH:10]1[C:25](=[O:26])[N:12]2[C:13]([C:22]([OH:24])=[O:23])=[C:14](OS(C)(=O)=O)[CH2:15][S:16][C@H:11]12)=[O:8]>C(O)C>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]([NH:9][CH:10]1[C:25](=[O:26])[N:12]2[C:13]([C:22]([OH:24])=[O:23])=[CH:14][CH2:15][S:16][C@H:11]12)=[O:8]

参加物

3

反応物 1

HCID 88662971HCID 88662971、化合物

生成物 1

HCID 70436618HCID 70436618、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A 200 mg. portion of 7-(thien-2-ylacetamido)-3-methanesulfonyloxyl-3-cephem-4-carboxylic acid was dissolved in a working fluid containing 2.5 mg./ml. of the starting compound, 35% by volume of ethanol, and 64% by volume of 1.0 molar pH 7.0 McIlvaine buffer. The measured pH of the working fluid was 7.5. The electrolysis was carried out as described in Example 1 in the same type of cell described in Example 1, and the product was worked up as described in Example 2 to obtain about 130 mg. of crude product. The product was converted to the methyl ester, and submitted to mass spectroscopy, which revealed the presence of molecular ions of mass 337 and 338, confirming that the desired product was obtained.

後処理

  1. additioncontaining 2.5 mg
  2. customto obtain about 130 mg

出典と根拠

ORDレコード
ord-2752ce02705b4e3eb6d41414307422b3
出典データセット
uspto-grants-1983_09
特許番号
US04402803

反応ノート

読み込み中…