Potassium Iodide → HCID 20402707、化合物

HRID 1995098ノート

反応式

HRID 1995098 の反応式
[C:1]([C:9]1[C:10]([NH:16][C:17](=[O:20])[CH2:18]Cl)=[CH:11][N:12]([CH3:15])[C:13]=1[CH3:14])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[I-:21].[K+]>C(O)C>[C:1]([C:9]1[C:10]([NH:16][C:17](=[O:20])[CH2:18][I:21])=[CH:11][N:12]([CH3:15])[C:13]=1[CH3:14])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 4875Potassium IodideHCID 20402708HCID 20402708、化合物

生成物 1

HCID 20402707HCID 20402707、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

N-(4-benzoyl-1,5-dimethyl(1H)pyrrol-3-yl)2-chloroacetamide (0.741 mole) and potassium iodide (1.62 mole) were refluxed in ethanol (3400 ml) for 5 hours with stirring. The reaction mixture was then cooled, the inorganic salts were filtered off and the solvent was evaporated under vacuum. The obtained residue was purified by washing first with water and then with cold ethanol. M.p. 135°-137° C. Yield 87%.

後処理

  1. temperatureThe reaction mixture was then cooled
  2. filtrationthe inorganic salts were filtered off
  3. customthe solvent was evaporated under vacuum
  4. customThe obtained residue was purified
  5. washby washing first with water

出典と根拠

ORDレコード
ord-5b0c6240e9054f30a69c9a3fee9ae5b8
出典データセット
uspto-grants-1983_09
特許番号
US04402970

反応ノート

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