4-Chloro-6-methylpyridine-2-carboxylic acid → HCID 178426117、化合物
反応式
[Cl:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([C:9]([OH:11])=O)[CH:3]=1.[NH2:12][C:13]1[NH:17][N:16]=[N:15][N:14]=1>>[NH:14]1[C:13]([NH:12][C:9]([C:4]2[CH:3]=[C:2]([Cl:1])[CH:7]=[C:6]([CH3:8])[N:5]=2)=[O:11])=[N:17][N:16]=[N:15]1参加物
3
実験手順
0.68 g of 4-chloro-6-methyl-2-pyridinecarboxylic acid, 0.67 g of N,N'-carbonyldiimidazole and 0.37 g of 5-aminotetrazole are treated in the same manner as described in Example 2. The crude product thus obtained is recrystallized from a mixture of dimethylformamide and ethanol, whereby 0.65 g of N-(5-tetrazolyl)-4-chloro-6-methyl-2-pyridinecarboxamide is obtained.
後処理
- customThe crude product thus obtained
- customis recrystallized from a mixture of dimethylformamide and ethanol
出典と根拠
- ORDレコード
- ord-a4cc4b8d7f424794ad10242e96356b48
- 出典データセット
- uspto-grants-1983_09
- 特許番号
- US04404214
反応ノート
読み込み中…