Benzoic acid, 2-chloro-6-nitro-, methyl ester → Methyl 2-amino-6-chlorobenzoate
反応式
[Cl:1][C:2]1[C:7]([C:8]([O:10][CH3:11])=[O:9])=[C:6]([N+:12]([O-])=O)[CH:5]=[CH:4][CH:3]=1.[H][H]>[Ni].CO>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]([NH2:12])[C:7]=1[C:8]([O:10][CH3:11])=[O:9]参加物
5
実験手順
4.5 gm (0.212 mol) of methyl 6-chloro-2-nitro-benzoate were hydrogenated with Raney nickel in 1.8 liters of methanol until the calculated amount of hydrogen was absorbed. The filtered reaction mixture was evaporated in vacuo, and the residue was distilled in vacuo.
後処理
- customwas absorbed
- customThe filtered reaction mixture
- customwas evaporated in vacuo
- distillationthe residue was distilled in vacuo
出典と根拠
- ORDレコード
- ord-ff8c8899ad384fc487339258c97eb69f
- 出典データセット
- uspto-grants-1983_09
- 特許番号
- US04404230
反応ノート
読み込み中…