2-Pyrrolidone → N-(hydroxyethoxyethoxyethyl)pyrrolidine
反応式
[NH:1]1[CH2:5][CH2:4][CH2:3][C:2]1=O.Cl[CH2:8][CH2:9][O:10][CH2:11][CH2:12][O:13][CH:14](O)[CH3:15].[OH-:17].[K+]>C(O)C>[OH:17][CH2:8][CH2:9][O:10][CH2:11][CH2:12][O:13][CH2:14][CH2:15][N:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1参加物
5
実験手順
A total of 295 g of pyrrolidone and 250 g of 2-chloroethoxyethoxyethanol in 750 ml of ethanol was refluxed for 5 hours. The reaction mixture was then treated with 106 g of KOH and refluxed for an additional hour. Filtration and distillation yielded 229 g of N-(hydroxyethoxyethoxyethyl)pyrrolidine (b.p.=145° C. at 3 mm).
後処理
- temperaturerefluxed for an additional hour
- filtrationFiltration and distillation
出典と根拠
- ORDレコード
- ord-022f33e858d94b358a17e7546382fa75
- 出典データセット
- uspto-grants-1983_09
- 特許番号
- US04405582
反応ノート
読み込み中…