関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1,3-dihydro-4-methyl-2H-imidazol-2-one | HCID 70935 | — |
| 反応物 | Veratroyl chloride | HCID 77070 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | Nitrobenzene | HCID 7416 | — |
| 生成物 | 4-(3,4-Dimethoxybenzoyl)-1,3-dihydro-2H-imidazol-2-one | HCID 20487561 | — |
反応手順
To a solution of 6.5 g of 1,3-dihydro-4-methyl-2H-imidazol-2-one and 14.6 g of aluminum chloride in 65 ml of nitrobenzene is added 17.6 g of 3,4-dimethoxybenzoyl chloride in portions. The mixture is stirred for 3 hours at 60° C., cooled and poured over ice water. The gummy solids are filtered and recrystallized twice from ethyl alcohol-water to afford the title compound. M.P. 257°-259° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04405635 |
|---|
| 出典データセット | uspto-grants-1983_09 |
|---|
| ORD ID | ord-6720dc5fc3df433ea6385c169bd2b31d |
|---|
| 出典メモ | uspto-grants-1983_09 |
|---|
