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Potassium Carbonate → 7-Benzyl-1-ethoxymethyl-3-methylxanthine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Chloromethyl ethyl ether | HCID 18523 | — |
| 反応物 | 7-Benzyl-3-methylxanthine | HCID 685630 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 7-Benzyl-1-ethoxymethyl-3-methylxanthine | HCID 19689145 | — |
反応手順
20 g (0.078 mol) of 7-benzyl-3-methylxanthine were stirred at 80° C. for 6 hours with 8.8 g (0.094 mol) of ethoxymethyl chloride and 13 g of potassium carbonate in 500 ml of absolute dimethylformamide, the mixture was filtered and concentrated, and the residue which remained was chromatographed (eluent: dichloromethane/methanol 20:1).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05728686 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-eadaded2a68a4a4683c2b0691e2f1aa0 |
| 出典メモ | uspto-grants-1998_03 |