Ethyl Acetate → 3-(1H-Pyrrolo[2,3-b]pyridin-5-yl)-azetidine-1-carboxylic acid tert-butyl ester

反応式

[Br:6][CH:7]([Br:8])[CH3:9].[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[N:17]1[CH2:18][CH:19]([I:21])[CH2:20]1.[CH3:32][C:33]([N:34]([CH3:35])[CH3:36])=[O:37].[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[Cl:1][C:2]([SiH3:3])([Cl:4])[Cl:5].[Cu:45][I:46].[I:22][c:23]1[cH:24][c:25]2[c:26]([n:27][cH:28]1)[nH:29][cH:30][cH:31]2.[Zn:44]>>[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[N:17]1[CH2:18][CH:19]([c:23]2[cH:24][c:25]3[c:26]([n:27][cH:28]2)[nH:29][cH:30][cH:31]3)[CH2:20]1