Toluene → 4-[6-(8-Cyclopentyl-6-methyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-pyridin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester

反応式

[C:21]([CH3:22])([CH3:23])([CH3:24])[O:25][C:26](=[O:27])[N:28]1[CH2:29][CH2:30][N:31]([c:34]2[cH:35][n:36][c:37]([NH2:40])[cH:38][cH:39]2)[CH2:32][CH2:33]1.[CH3:41][CH2:42][O:43][CH2:44][CH3:45].[CH3:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[CH:1]1([n:6]2[c:7](=[O:20])[c:8]([CH3:19])[cH:9][c:10]3[c:11]2[n:12][c:13]([S:16]([CH3:17])=[O:18])[n:14][cH:15]3)[CH2:2][CH2:3][CH2:4][CH2:5]1>>[CH:1]1([n:6]2[c:7](=[O:20])[c:8]([CH3:19])[cH:9][c:10]3[c:11]2[n:12][c:13]([NH:40][c:37]2[n:36][cH:35][c:34]([N:31]4[CH2:30][CH2:29][N:28]([C:26]([O:25][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:27])[CH2:33][CH2:32]4)[cH:39][cH:38]2)[n:14][cH:15]3)[CH2:2][CH2:3][CH2:4][CH2:5]1