関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Toluene | HCID 1140 | — |
| 反応物 | Dichloromethane | HCID 6344 | — |
| 反応物 | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| 反応物 | Magnesium Bromide | HCID 82241 | — |
| 反応物 | Dipyrromethane | HCID 140814 | — |
| 生成物 | 21H,22H-Porphine | HCID 137705241 | — |
反応手順
Synthesis of Mg-1 via 1,9-Diformyldipyrromethane. By following the general procedure, a sample of DBU (0.750 mL, 5.00 mmol) was added dropwise to a suspension of 3 (36 mg, 0.25 mmol) and 4 (50 mg, 0.25 mmol) in toluene (5 mL). MgBr2 (276 mg, 1.5 mmol, 3.00 mol equiv) was added to the reaction mixture in a single portion. The reaction mixture was heated to 115° C. (preheated oil bath temperature 115° C.) with exposure to air for 36 h. Column chromatography (alumina, grade V, CH2Cl2) afforded Mg-1 in 18% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07745618B2 |
|---|
| 出典データセット | uspto-grants-2010_06 |
|---|
| ORD ID | ord-658e13e130fc421b9eae6990c9f2bbc8 |
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| 出典メモ | uspto-grants-2010_06 |
|---|
