Hydrochloric Acid → methyl 1H-tetrazol-1-ylacetate

HRID 20268ノート

反応式

HRID 20268 の反応式
[N:1]1([CH2:6][C:7]([OH:9])=[O:8])[CH:5]=[N:4][N:3]=[N:2]1.Cl.O1CCOC[CH2:12]1>CO>[N:1]1([CH2:6][C:7]([O:9][CH3:12])=[O:8])[CH:5]=[N:4][N:3]=[N:2]1

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 5432071-Tetrazolylacetic acid

生成物 1

HCID 3153776methyl 1H-tetrazol-1-ylacetate

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A mixture of tetrazol-1-yl acetic acid (5 g, 39 mmol) and 4M hydrochloric acid in dioxan (100 μL) in methanol (50 mL) was heated under reflux for 18 hours. The cooled mixture was evaporated under reduced pressure to provide the title compound.

後処理

  1. temperaturewas heated
  2. temperatureunder reflux for 18 hours
  3. customThe cooled mixture was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-2eec8cc3221c4243826d62a42e0801a2
出典データセット
uspto-grants-2010_06
特許番号
US07745630B2

反応ノート

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