Benzyl Bromide → 7-Benzyl-3-ethyl-3,7-dihydro-1H-purine-2,6-dione

HRID 2029ノート

反応式

HRID 2029 の反応式
[CH2:1]([N:3]1[C:11]2[N:10]=[CH:9][NH:8][C:7]=2[C:6](=[O:12])[NH:5][C:4]1=[O:13])[CH3:2].[CH2:14](Br)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.C(=O)([O-])[O-].[K+].[K+]>O>[CH2:14]([N:8]1[C:7]2[C:6](=[O:12])[NH:5][C:4](=[O:13])[N:3]([CH2:1][CH3:2])[C:11]=2[N:10]=[CH:9]1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

参加物

5

反応物 3

HCID 7498Benzyl BromideHCID 11430Potassium CarbonateHCID 3507373-ethylxanthine

生成物 1

HCID 220073037-Benzyl-3-ethyl-3,7-dihydro-1H-purine-2,6-dione

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

18 g (0.1 mol) of 3-ethylxanthine were stirred at 60° C. for 2 hours with 19.2 g (0.11 mol) of benzyl bromide and 15.2 g (0.11 mol) of potassium carbonate. The reaction solution was transferred to an Edenmeyer flask and treated with 1000 ml of water. The precipitate was filtered off with suction, washed several times with warm water and dried at 50° C. under reduced pressure.

後処理

  1. filtrationThe precipitate was filtered off with suction
  2. washwashed several times with warm water
  3. customdried at 50° C. under reduced pressure

出典と根拠

ORDレコード
ord-61cce6857443438ba8ad80c482010310
出典データセット
uspto-grants-1998_03
特許番号
US05728686

反応ノート

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