化工社化工社 化学情報印刷レポート · 研究参考用
Methyl iodide → 1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl iodide | HCID 6328 | — |
| 反応物 | 1-Ethylpiperidin-4-one | HCID 77159 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide | HCID 11097568 | 84.9% |
反応手順
To a solution of 1-ethyl-4-oxopiperidine (25 g, 0.197 mol) in acetone (250 ml) at RT in a water bath was added methyl iodide (15.5 ml, 0.25 mol) at such a rate to keep the temperature below 30° C. The mixture was filtered and the precipitate washed with acetone and dried to yield 1-ethyl-1-methyl-4-oxopiperidinium iodide (45 g) (LC/MS: Rt 0.38, [M+H]+ 143).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07745638B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-ae618f52af61445c9898a909d30788df |
| 出典メモ | uspto-grants-2010_06 |