化工社化工社 化学情報印刷レポート · 研究参考用
Vinyl Acetate → 3,3-Dimethyl-1-vinyloxybutane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Vinyl Acetate | HCID 7904 | — |
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 反応物 | 3,3-Dimethyl-1-butanol | HCID 12233 | — |
| 触媒 | Chloro(1,5-cyclooctadiene)iridium(I) dimer | HCID 6436381 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | 3,3-Dimethyl-1-vinyloxybutane | HCID 66368015 | — |
反応手順
Add chloro(1,5-cyclooctadiene)iridium(I) dimer (0.39 g, 0.59 mmol) to 3,3-dimethylbutan-1-ol (3.00 g, 29.35 mmol), vinyl acetate (10.11 g, 117.42 mmol) and sodium carbonate (1.87 g, 17.61 mmol) in benzene (10 mL) at room temperature. Boil under nitrogen 12 hours. Cool to room temperature and filter. Distill the filtrate and collect fraction boiling ˜125° C.-130° C. Flush through a silica gel pad with hexanes and concentrate to provide the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07745438B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-226ce7882d634d20897871d2dacfff1a |
| 出典メモ | uspto-grants-2010_06 |