tert-Butyl 4-(4-aminophenyl)piperidine-1-carboxylate → 4-{4-[8-(4-Cyano-phenyl)-[1,2,4]-triazolo[1,5-a]pyridin-2-ylamino]-phenyl}-piperidine-1-carboxylic acid tert-butyl ester

反応式

[C:19]([CH3:20])([CH3:21])([CH3:22])[O:23][C:24](=[O:25])[N:26]1[CH2:27][CH2:28][CH:29]([c:32]2[cH:33][cH:34][c:35]([NH2:38])[cH:36][cH:37]2)[CH2:30][CH2:31]1.[Cl:1][c:2]1[n:3][n:4]2[c:5]([c:6](-[c:10]3[cH:11][cH:12][c:13]([C:16]#[N:17])[cH:14][cH:15]3)[cH:7][cH:8][cH:9]2)[n:18]1>>[c:2]1([NH:38][c:35]2[cH:34][cH:33][c:32]([CH:29]3[CH2:28][CH2:27][N:26]([C:24]([O:23][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:25])[CH2:31][CH2:30]3)[cH:37][cH:36]2)[n:3][n:4]2[c:5]([c:6](-[c:10]3[cH:11][cH:12][c:13]([C:16]#[N:17])[cH:14][cH:15]3)[cH:7][cH:8][cH:9]2)[n:18]1

参加物

反応物 2

HCID 21940085tert-Butyl 4-(4-aminophenyl)piperidine-1-carboxylate

HCID 674815292-Chloro-8-(4-cyano-phenyl)-[1,2,4]-triazolo[1,5-a]pyridine

生成物 1

HCID 596124024-{4-[8-(4-Cyano-phenyl)-[1,2,4]-triazolo[1,5-a]pyridin-2-ylamino]-phenyl}-piperidine-1-carboxylic acid tert-butyl ester

出典と根拠

ORDレコード: ord-b33dc92c096d44518049f9cf053e82dc
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…