2-Ethynylaniline → 2-(2-tert-Butyl-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)-phenylamine

HRID 2042174ノート

反応式

HRID 2042174 の反応式
Br[C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:10]=2)[CH:7]=1.[C:15]([C:17]1[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=1[NH2:19])#[CH:16]>>[C:11]([C:9]1[CH:10]=[C:5]2[N:4]=[CH:3][C:2]([C:16]#[C:15][C:17]3[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=3[NH2:19])=[CH:7][N:6]2[N:8]=1)([CH3:14])([CH3:13])[CH3:12]

参加物

3

反応物 2

HCID 41539052-EthynylanilineHCID 583166976-Bromo-2-tert-butylpyrazolo[1,5-a]pyrimidine

生成物 1

HCID 532474542-(2-tert-Butyl-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)-phenylamine

実験手順

The title compound, light yellow solid, MS: m/e=291.2 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-tert-butyl-pyrazolo[1,5-a]pyrimidine (example 9, step 1) and 2-ethynylaniline.

出典と根拠

ORDレコード
ord-34329dda937b4d709111f7207954fd0d
出典データセット
uspto-grants-2013_11
特許番号
US08586581B2

反応ノート

読み込み中…