関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | Naphthalene-1-carbonyl naphthalene-1-carboxylate | HCID 350399 | — |
| 生成物 | 5-Bromobenzo[de]isochromene-1,3-dione | HCID 3907491 | 22.7% |
反応手順
Naphthalic anhydride 20 (100 g, 505 mmol) was slurried in c-nitric acid (70%, 2.0 L) and heated to 50° C. Bromine (19.4 mL, 379 mmol) was added evenly over 10 min, and the resulting solution was held at 50° C. for 4 h before cooling to 0° C. The resulting solid was isolated by filtration and dried in vacuo to provide the titled compound 21 (23.8 g, 17%) as a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08586550B2 |
|---|
| 出典データセット | uspto-grants-2013_11 |
|---|
| ORD ID | ord-23eed28de70f454f9da258c8edec9932 |
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| 出典メモ | uspto-grants-2013_11 |
|---|
