Ethanol → 1-Hydroxy-1H-1,2,3-triazole-4-carboxylic Acid
反応式
C([O:3][C:4]([C:6]1[N:7]=[N:8][N:9]([OH:11])[CH:10]=1)=[O:5])C.CCO.O.[OH-].[Li+]>O>[OH:11][N:9]1[CH:10]=[C:6]([C:4]([OH:5])=[O:3])[N:7]=[N:8]1参加物
5
実験手順
1-Hydroxy-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester (2.0 g, 13 mmol) and EtOH (25 mL) were combined with a pre-dissolved solution of lithium hydroxide monohydrate (1.6 g, 38.2 mmol) and water (10 mL), and stirred at room temperature for 4 hours. The mixture was partially concentrated and acidified with HCl to cause precipitation. The solid was filtered and dried under vacuum to yield the title compound (1.3 g).
後処理
- concentrationThe mixture was partially concentrated
- customprecipitation
- filtrationThe solid was filtered
- customdried under vacuum
出典と根拠
- ORDレコード
- ord-d06c5fb256e44da595cd33457ae84bbf
- 出典データセット
- uspto-grants-2013_11
- 特許番号
- US08586536B2
反応ノート
読み込み中…