(S)-4-Hydroxymethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester → HCID 70654325、化合物

HRID 2046188

反応式

HRID 2046188 の反応式
C(OC(C1NN=C(COC2C=CC=CC=2)C=1)=O)C.CC1(C)OC[C@H](CO)N1C(OC(C)(C)C)=O.[C:35]([O:39][C:40]([N:42]1[C@H:46]([CH2:47][N:48]2[C:52]([C:53]([O:55][CH2:56][CH3:57])=[O:54])=[CH:51][C:50]([CH2:58][O:59][C:60]3[CH:65]=[CH:64][CH:63]=[CH:62][CH:61]=3)=[N:49]2)[CH2:45][O:44][C:43]1([CH3:67])[CH3:66])=[O:41])([CH3:38])([CH3:37])[CH3:36]>>[C:35]([O:39][C:40]([N:42]1[C@@H:46]([CH2:47][N:48]2[C:52]([C:53]([O:55][CH2:56][CH3:57])=[O:54])=[CH:51][C:50]([CH2:58][O:59][C:60]3[CH:61]=[CH:62][CH:63]=[CH:64][CH:65]=3)=[N:49]2)[CH2:45][O:44][C:43]1([CH3:66])[CH3:67])=[O:41])([CH3:36])([CH3:37])[CH3:38]

参加物

4

反応物 3

HCID 11053463(S)-4-Hydroxymethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl esterHCID 70654332HCID 70654332、化合物HCID 178469067HCID 178469067、化合物

生成物 1

HCID 70654325HCID 70654325、化合物

実験手順

The compound was prepared from 5-phenoxymethyl-2H-pyrazole-3-carboxylic acid ethyl ester and (S)-1-boc-2,2-dimethyl-4-hydroxymethyl-oxazolidine using the method described in the preceding example 29 (R)-4-(5-ethoxycarbonyl-3-phenoxymethyl-pyrazol-1-ylmethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester.

出典と根拠

ORDレコード
ord-e1cfb0ccc921469891d6216e972cffe1
出典データセット
uspto-grants-2013_11
特許番号
US08592422B2

関連ノート

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