1-(cyclopropylmethyl)-N-methylpiperidine-4-amine → 2-(5-amino-4,6-dimethylpyrimidine-2-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylpropanamide

HRID 2046362

反応式

HRID 2046362 の反応式
C(OC([NH:8][C:9]1[C:10]([CH3:22])=[N:11][C:12]([O:16][CH:17]([CH3:21])[C:18]([OH:20])=O)=[N:13][C:14]=1[CH3:15])=O)(C)(C)C.[CH:23]1([CH2:26][N:27]2[CH2:32][CH2:31][CH:30]([NH:33][CH3:34])[CH2:29][CH2:28]2)[CH2:25][CH2:24]1>>[NH2:8][C:9]1[C:14]([CH3:15])=[N:13][C:12]([O:16][CH:17]([CH3:21])[C:18]([N:33]([CH:30]2[CH2:29][CH2:28][N:27]([CH2:26][CH:23]3[CH2:25][CH2:24]3)[CH2:32][CH2:31]2)[CH3:34])=[O:20])=[N:11][C:10]=1[CH3:22]

参加物

3

実験手順

The title compound was synthesized from Compound 12 and 1-(cyclopropylmethyl)-N-methyl-piperidine-4-amine in the same manner as in Example 64.

出典と根拠

ORDレコード
ord-2e406cfd1ef54c22b067a0ac0c88b3d8
出典データセット
uspto-grants-2013_11
特許番号
US08592435B2

関連ノート

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