1-(2,4-Dichloro-6-(2-(isopropylsulfonyl)phenylamino)pyrimidin-5-yl)ethanone → Tert-butyl 4-(4-(5-acetyl-4-chloro-6-(2-(isopropylsulfonyl)phenylamino)pyrimidin-2-ylamino)-5-isopropoxy-2-methylphenyl)piperidine-1-carboxylate
反応式
Cl[C:2]1[N:7]=[C:6]([Cl:8])[C:5]([C:9](=[O:11])[CH3:10])=[C:4]([NH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[S:19]([CH:22]([CH3:24])[CH3:23])(=[O:21])=[O:20])[N:3]=1.[C:25]([O:29][C:30]([N:32]1[CH2:37][CH2:36][CH:35]([C:38]2[CH:43]=[C:42]([O:44][CH:45]([CH3:47])[CH3:46])[C:41]([NH2:48])=[CH:40][C:39]=2[CH3:49])[CH2:34][CH2:33]1)=[O:31])([CH3:28])([CH3:27])[CH3:26]>CCO>[C:9]([C:5]1[C:6]([Cl:8])=[N:7][C:2]([NH:48][C:41]2[C:42]([O:44][CH:45]([CH3:47])[CH3:46])=[CH:43][C:38]([CH:35]3[CH2:34][CH2:33][N:32]([C:30]([O:29][C:25]([CH3:26])([CH3:28])[CH3:27])=[O:31])[CH2:37][CH2:36]3)=[C:39]([CH3:49])[CH:40]=2)=[N:3][C:4]=1[NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[S:19]([CH:22]([CH3:24])[CH3:23])(=[O:21])=[O:20])(=[O:11])[CH3:10]参加物
4
