7-Chloro-5-(1,4-dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidine → 7-Chloro-5-(1,4-dioxaspiro[4.5]decan-7-yl)pyrazolo[1,5-a]pyrimidine

HRID 2047089ノート

反応式

HRID 2047089 の反応式
[Cl:1][C:2]1[N:7]2[N:8]=[CH:9][CH:10]=[C:6]2[N:5]=[C:4]([CH:11]2[CH2:20][CH2:19][C:14]3(OCCO3)[CH2:13][CH2:12]2)[CH:3]=1.[O:21]1C2(CCCC(C3C=C(O)N4N=CC=C4N=3)C2)[O:24][CH2:23][CH2:22]1.O1C2(CCC(C3C=C(O)N4N=CC=C4N=3)CC2)OCC1>>[Cl:1][C:2]1[N:7]2[N:8]=[CH:9][CH:10]=[C:6]2[N:5]=[C:4]([CH:11]2[CH2:12][CH2:13][CH2:14][C:19]3([O:24][CH2:23][CH2:22][O:21]3)[CH2:20]2)[CH:3]=1

参加物

4

反応物 3

HCID 866647817-Chloro-5-(1,4-dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidineHCID 178515484HCID 178515484、化合物HCID 178515508HCID 178515508、化合物

生成物 1

HCID 866647827-Chloro-5-(1,4-dioxaspiro[4.5]decan-7-yl)pyrazolo[1,5-a]pyrimidine

実験手順

7-Chloro-5-(1,4-dioxaspiro[4.5]decan-7-yl)pyrazolo[1,5-a]pyrimidine is synthesized in a manner similar to the synthesis of 7-chloro-5-(1,4-dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidine, but with 5-(1,4-dioxaspiro[4.5]decan-7-yl)pyrazolo[1,5-a]pyrimidin-7-ol substituted for 5-(1,4-dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidin-7-ol.

出典と根拠

ORDレコード
ord-6dbfdc92dee44788b21c4556076ed0c4
出典データセット
uspto-grants-2013_11
特許番号
US08591943B2

反応ノート

読み込み中…