5-(1,4-Dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidin-7-amine → HCID 66733391、化合物

HRID 2047094ノート

反応式

HRID 2047094 の反応式
[NH2:1][C:2]1[N:7]2[N:8]=[CH:9][CH:10]=[C:6]2[N:5]=[C:4]([CH:11]2[CH2:16][CH2:15][C:14](=[O:17])[CH2:13]C2)[CH:3]=1.O1C2(CCC(C3C=C(N)N4N=CC=C4N=3)C2)OCC1.O1C2(CCC(C3C=C(N)N4N=CC=C4N=3)CC2)OCC1>>[NH2:1][C:2]1[N:7]2[N:8]=[CH:9][CH:10]=[C:6]2[N:5]=[C:4]([CH:11]2[CH2:16][CH2:15][C:14](=[O:17])[CH2:13]2)[CH:3]=1

参加物

4

反応物 3

HCID 667334895-(1,4-Dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidin-7-amineHCID 667338125-(1,4-Dioxaspiro[4.4]nonan-7-yl)pyrazolo[1,5-a]pyrimidin-7-amineHCID 66733850HCID 66733850、化合物

生成物 1

HCID 66733391HCID 66733391、化合物

実験手順

3-(7-Aminopyrazolo[1,5-a]pyrimidin-5-yl)cyclopentanone was synthesized in a manner similar to the synthesis of 4-(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)cyclohexanone, but 5-(1,4-dioxaspiro[4.4]nonan-7-yl)pyrazolo[1,5-a]pyrimidin-7-amine substituted for 5-(1,4-dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidin-7-amine.

出典と根拠

ORDレコード
ord-d44e04248ecc42aba4a3d6bfb4193790
出典データセット
uspto-grants-2013_11
特許番号
US08591943B2

反応ノート

読み込み中…