N-Methylisobutylamine → 2-(Isobutyl-methyl-amino)-6-methyl-isonicotinic acid
反応式
[CH2:1](N(CC)C1C=C(C=C(C)N=1)C(O)=O)C.Cl[C:17]1[CH:18]=[C:19]([CH:23]=[C:24](Cl)[N:25]=1)[C:20]([OH:22])=[O:21].[CH2:27]([NH:31][CH3:32])[CH:28]([CH3:30])[CH3:29]>>[CH2:27]([N:31]([CH3:32])[C:17]1[CH:18]=[C:19]([CH:23]=[C:24]([CH3:1])[N:25]=1)[C:20]([OH:22])=[O:21])[CH:28]([CH3:30])[CH3:29]参加物
4
実験手順
The title compound is prepared in analogy to 2-diethylamino-6-methyl-isonicotinic acid starting from 2,6-dichloro-isonicotinic acid and N-isobutyl-N-methylamine; LC-MS: tR=0.50*min, [M+1]+=223.28.
出典と根拠
- ORDレコード
- ord-54bd1373234d47c6bf6c87bee51fde5d
- 出典データセット
- uspto-grants-2013_11
- 特許番号
- US08592460B2
反応ノート
読み込み中…